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Elucidation of the Genomic Nucleotide Sequence of Bovine Coronavirus and Analysis of Cryptic Leader mRNA Fusion Sites

Elucidation of the Genomic Nucleotide Sequence of Bovine Coronavirus and Analysis of Cryptic Leader mRNA Fusion Sites

  • Vladimir N. Chouljenko3,
  • Timothy P. Foster3,
  • Xiaoqing Lin3,
  • Johannes Storz3 &
  • …
  • Konstantin G. Kousoulas3 
  • Chapter
  • 335 Accesses

  • 3 Citations

Part of the Advances in Experimental Medicine and Biology book series (AEMB,volume 494)

Abstract

Over the last few years numerous respiratory bovine coronaviruses (RBCV) were isolated from respiratory infections of cattle including two shipping fever epizootics (Storz et al., 1996; Storz et al., 2000). The RBCV strain 98TXSF-110-LU (LU) and the enteric strain 98TXSF-110-ENT (ENT) were isolated from lung and intestinal samples, respectively, from an animal experiencing fatal respiratory disease during a 1998 shipping fever epizootic. We obtained and compared the entire genomic sequences of the LU and ENT isolates to delineate nucleotide (nt) and amino acid (aa) differences between them. In addition, we analyzed the leader-mRNA junction sequences of the S and 12.7 kDa mRNAs specified by different BCV strains.

Keywords

  • Single Nucleotide Substitution
  • Junction Sequence
  • Fusion Site
  • Entire Genomic Sequence
  • Genomic Nucleotide Sequence

These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Author information

Authors and Affiliations

  1. Department of Veterinary Microbiology and Parasitology, School of Veterinary Medicine Louisiana State University, Baton Rouge, LA, 70803, USA

    Vladimir N. Chouljenko, Timothy P. Foster, Xiaoqing Lin, Johannes Storz & Konstantin G. Kousoulas

Authors
  1. Vladimir N. Chouljenko
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  2. Timothy P. Foster
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  3. Xiaoqing Lin
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  4. Johannes Storz
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  5. Konstantin G. Kousoulas
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Editor information

Editors and Affiliations

  1. University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA

    Ehud Lavi & Susan R. Weiss & 

  2. Philadelphia College of Osteopathic Medicine, Philadelphia, Pennsylvania, USA

    Susan T. Hingley

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© 2001 Springer Science+Business Media New York

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Chouljenko, V.N., Foster, T.P., Lin, X., Storz, J., Kousoulas, K.G. (2001). Elucidation of the Genomic Nucleotide Sequence of Bovine Coronavirus and Analysis of Cryptic Leader mRNA Fusion Sites. In: Lavi, E., Weiss, S.R., Hingley, S.T. (eds) The Nidoviruses. Advances in Experimental Medicine and Biology, vol 494. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1325-4_7

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  • DOI: https://doi.org/10.1007/978-1-4615-1325-4_7

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  • Print ISBN: 978-1-4613-5498-7

  • Online ISBN: 978-1-4615-1325-4

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