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Coronary Heart Disease and Risk Factors in Asian Indians

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Diabetes and Cardiovascular Disease

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 498))

Abstract

Traditionally individuals living in the Indian subcontinent (India, Pakistan, and Bangladesh) were considered to have a low prevalence of coronary heart disease (CHD). However, recent epidemiological studies have shown that Asian Indians who have migrated to western countries as well as those living in urban areas of the Indian subcontinent have a higher prevalence of CHD than do Caucasians of European ancestry1– 7. This apparent excess of CHD could relate to environmental or genetic factors. Since lifestyle, including different levels of exercise, is shown to affect risk factors for CHD in Caucasians, it is likely that the adoption of the western lifestyle by Indians living in the urban areas of the Indian subcontinent or migrants to western countries could increase their risk for CHD. Asia is undergoing unprecedented economic growth, technological advances, and urbanization resulting in westernization of diet and reduction in physical activity. With these changes, it is likely that the prevalence of traditional risk factors for heart disease like hypercholesterolemia, hypertension and diabetes will increase. As a consequence, it is expected that CHD and morbidity and mortality associated with it will increase exponentially in the near future. A two-fold increase in the number of deaths related to CHD has been projected from year 1985 to year 2015. In men, the projected death rates per 100,000 population are 145 in 1985 and 253 in 2000 and 295 in 2015, while in women, the projected rates are 126, 204 and 239, respectively8,9. CHD is likely to account for at least 33.5% of total deaths by the year 2015 and would replace infectious disease as a number one killer in Indians.

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Author information

Authors and Affiliations

  1. Department of Internal Medicine, University of Texas Southwestern Medical Center, and Department of Veterans Affairs Medical Center, Dallas, TX

    Manisha Chandalia

  2. Cardiology Division, Department of Medicine, UCSF School of Medicine, Fresno, CA

    Prakash C. Deedwania

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  1. Manisha Chandalia
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  2. Prakash C. Deedwania
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Editor information

Editors and Affiliations

  1. Diabetes Research and Treatment Centre, Winnipeg, Canada

    Aubie Angel

  2. St. Boniface Research Centre, Winnipeg, Canada

    Naranjan Dhalla , Grant Pierce  & Pawan Singal ,  & 

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Chandalia, M., Deedwania, P.C. (2001). Coronary Heart Disease and Risk Factors in Asian Indians. In: Angel, A., Dhalla, N., Pierce, G., Singal, P. (eds) Diabetes and Cardiovascular Disease. Advances in Experimental Medicine and Biology, vol 498. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1321-6_5

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  • DOI: https://doi.org/10.1007/978-1-4615-1321-6_5

  • Publisher Name: Springer, Boston, MA

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  • Online ISBN: 978-1-4615-1321-6

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