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Hemolytic Capacity, Properties, and Activation Requirements of Cobra Venom Factor-Treated Chicken Serum

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Phylogenetic Perspectives on the Vertebrate Immune System

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 484))

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Abstract

In contrast to the depletion of complement (C’) activity which occurs following the addition of cobra venom factor (CoVF) to mammalian serum, we have found that CoVF-treated chicken serum retains its lytic potential. We report herein some of the lytic and physiochemical properties of CoVF-treated chicken serum, and compare its activity to that of similarly treated turtle and bullfrog sera.

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References

  • Ohta H, Yoshikawa Y, Kai C, Yamanouchi K, Okada H. Lysis of horse red blood cells mediated by antibody-dependent activation of the alternative pathway of complement. Immunology, 1984; 49:29–35.

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  • Ohta H, Yoshikawa Y, Kai C, Yamanouchi K, Taniguchi H, Komine K-I., Ishijima Y, Okada H. Effect of complement depletion by cobra venom factor in fowlpox virus infection in chickens and chicken embryos. J. Virology, 1986; 57:670–673.

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© 2001 Springer Science+Business Media New York

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Koppenheffer, T.L. (2001). Hemolytic Capacity, Properties, and Activation Requirements of Cobra Venom Factor-Treated Chicken Serum. In: Beck, G., Sugumaran, M., Cooper, E.L. (eds) Phylogenetic Perspectives on the Vertebrate Immune System. Advances in Experimental Medicine and Biology, vol 484. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1291-2_19

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  • DOI: https://doi.org/10.1007/978-1-4615-1291-2_19

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5481-9

  • Online ISBN: 978-1-4615-1291-2

  • eBook Packages: Springer Book Archive

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