Suppression of the Drosophila Cellular Immune Response by Ganaspis xanthopoda

  • Hsiling Chili
  • Richard Paul Sorrentino
  • Shubha Govind
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 484)


The cellular immune response of larvae of Drosophila melanogaster is mediated by two types of hemocyte. Plasmatocytes are small, round, and phagocytic hemocytes that engulf small particles, such as bacteria. When large objects, such as eggs of parasitoid wasps, are introduced into the larval hemocoel, plasmatocytes differentiate into larger, flat, and adhesive lamellocytes. Lamellocytes adhere to one another and wrap around the foreign body, forming capsules. These capsules are often melanized by the second type of hemocyte, called crystal cells, which house enzymes for melanization reactions (Rizki and Rizki, 1984). The capsules render the parasite inert and allow the host to survive. In the larva, plasmatocytes and crystal cells originate in the lymph gland, which is the hematopoietic organ in Drosophila. (Shrestha and Gateff, 1982).


Cellular Immune Response Anterior Lobe Posterior Lobe Parasitoid Wasp Hemolymph Sample 
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Copyright information

© Springer Science+Business Media New York 2001

Authors and Affiliations

  • Hsiling Chili
    • 1
  • Richard Paul Sorrentino
    • 1
    • 2
  • Shubha Govind
    • 1
    • 2
  1. 1.The City CollegeCity UniversityNew York
  2. 2.Graduate School and University CenterCity UniversityNew York

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