Several protocols are being followed presently to demonstrate the effectiveness of BNCT for treating brain tumors. In these, a compound containing B is injected into the patient and the B selectively collects in the tumor prior to neutron irradiation. For deep brain tumors, when the dose to healthy brain is taken to a maximum limit of tolerance = 12.5 Gy-Eq, the dose to the tumor at the midline of the head may be marginal for sterilizing all cancerous cells. Sometimes, injecting more of the same B compound to increase the dose to the tumor is not practical. The present study considers injecting a second, but different, compound with a different agent which targets the tumor.1 Here, agents means different elements and not several compounds containing B.
KeywordsBoron Fractionation Porphyrin Auger Gadolinium
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