Dietary Intervention Strategies: Validity, Execution and Interpretation of Outcomes
Experimental research designs that use single chemical entities have been the cornerstone of careful scientific research. Therefore the use of total diet patterns, or whole foods, which contain hundreds of chemical components, would appear to lack sufficient control to yield productive information. However, cancer prevention and control may be an area where well-designed diet intervention strategies may be an efficient research approach. This chapter will present arguments for the necessity of diet and whole food supplementation research studies and descriptions of strategies for their implementation. Additionally, the components of effective diet intervention studies will be discussed. Whether the research involves cell media, animal diets or human diets, the whole diet should be considered an important factor in any research design where the ultimate aim is cancer prevention and control.
KeywordsCancer Prevention Flaxseed Diet Control Feeding Study Polyp Prevention Trial Nuclear Aberration
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