Headspace—Gas Chromatography

An Ideal Technique for Sampling Volatiles Present in Non-Volatile Matrices
  • Leslie S. Ettre
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 488)


After a brief overview of the techniques of static and dynamic headspace sampling and examples are given for the dynamic method (“purge and trap”). With respect to static headspace—gas chromatography (HS-GC) the theoretical background of the technique and the principles of the existing instruments are outlined. Five questions related to static HS-GC are discussed in more detail: trace analysis; ultratrace analysis with cryogenic enhancement of the analytes and elimination of the possible effect of excess water vapor in the sample; sample modification by carrying out reactions in the sample vial; non-equilibrium static HS-GC; and pattern analysis by HS-GC.


Potato Chip Headspace Sampling Coffee Powder Butyric Acid Methyl Ester Acetic Acid Methyl Ester 
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Copyright information

© Springer Science+Business Media New York 2001

Authors and Affiliations

  • Leslie S. Ettre
    • 1
  1. 1.Department of Chemical EngineeringYale UniversityNew Haven

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