Application of Noninvasive Doppler Echocardiographic Measurement of Coronary Flow Reserve
The preceding chapter described the application of coronary flow reserve measured by means of invasive techniques, which are of limited use. This chapter will focus on noninvasive tools used to assess coronary flow reserve in a wide spectrum of clinical settings. At present two noninvasive techniques are predominantly applied: Doppler echocardiography (transthoracic imaging is the technique, which develops most dynamically) and PET. Transthoracic Doppler echocardiography is rapidly gaining appreciation and it has become a popular tool evolving from a research to diagnostic technique applied on a large scale in everyday practice. In one of the numerous institutions performing transthoracic Doppler echocardiography (111), almost 1000 measurements of coronary flow reserve have been made in various cardiovascular diseases and using various pharmacological agents: vasodilators (dipyridamole, adenosine) and dobutamine, which increases myocardial oxygen demand.
KeywordsIschemia Estrogen Adenosine Luminal Cardiomyopathy
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