Abstract
In peripheral circulation oxygen extraction from perfusing blood is as low as 25%. In contrast, the amount of oxygen extracted by myocardium during a passage of blood through the coronary circulation is very high i.e. 70% in resting conditions. Consequently, during stress testing myocardial oxygen extraction may increase only slightly. For this reason myocardial oxygen supply depends mainly on the efficiency of the coronary vasodilatation augmenting the coronary blood flow to match the increasing myocardial metabolic demand. Pharmacological vasodilatation increasing coronary blood flow in relation to baseline value determines coronary flow reserve.
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© 2002 Springer Science+Business Media New York
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Petkow-Dimitrow, P. (2002). The Range of Normal Values for Coronary Flow Reserve and Lesion-Specific Physiological Measurements. In: Coronary flow reserve - measurement and application: Focus on transthoracic Doppler echocardiography. Basic Science for the Cardiologist, vol 13. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1125-0_2
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DOI: https://doi.org/10.1007/978-1-4615-1125-0_2
Publisher Name: Springer, Boston, MA
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