Non-Functioning Pituitary Tumours

  • R. N. Clayton
Part of the Endocrine Updates book series (ENDO, volume 18)


Sporadic pituitary tumours account for about 10% of all intracranial tumours (1). These are generally benign tumours although about 50% show histological evidence of invasion of the capsule or into surrounding structures (2). Between 0.1-0.2% of adenomas develop into frank carcinomas defined by metastatic spread, usually within the central nervous system but occasionally more distally (3,4). The peak incidence is between ages 30-60 years, being somewhat earlier in women (20-45 years) than in men (35-60 years) due to the greater frequency of prolactinomas in young women (5,6). Pituitary tumours are rare below the age of 20 years when the vast majority (86%) are prolactinomas, or corticotrophinomas (10%) (5).


Pituitary Adenoma Pituitary Tumour Diabetes Insipidus Multiple Endocrine Neoplasia Type Pituitary Carcinoma 
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Copyright information

© Springer Science+Business Media New York 2002

Authors and Affiliations

  • R. N. Clayton
    • 1
  1. 1.Department of MedicineSchool of Postgraduate Medicine, Keele University, Stoke on TrentStaffordshire

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