Federation of Brain Data through Knowledge-guided Mediation

  • Maryann E. Martone
  • Amarnath Gupta
  • Bertram Ludäscher
  • Ilya Zaslavsky
  • Mark H. Ellisman

Abstract

In this chapter, we describe a data integration framework for multi-resolution data and some of the tools we have created for achieving integration of distributed data sources. The chapter is divided into two parts. In the first part, we describe a recently developed database for high resolution 3D data on cell structure and protein localization, the Cell Centered Database or CCDB. In the second part, we describe how we can link data sources such as the CCDB to other databases using a mediation-based approach. By incorporating additional knowledge into the system, we are able to link together sources that are related conceptually, even if they do not contain similar elements in their schemata. For each of the tools and resources described, we indicate its current state of development and availability.

Key words

database electron tomography protein localization confocal microscopy electron microscopy 

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Copyright information

© Springer Science+Business Media New York 2003

Authors and Affiliations

  • Maryann E. Martone
    • 1
  • Amarnath Gupta
    • 2
  • Bertram Ludäscher
    • 2
  • Ilya Zaslavsky
    • 2
  • Mark H. Ellisman
    • 1
    • 2
  1. 1.National Center for Microscopy and Imaging Research and Department of NeurosciencesUniversity of California, San DiegoSan DiegoUSA
  2. 2.San Diego Supercomputer CenterUniversity of California, San DiegoSan DiegoUSA

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