Treatment of Ventilator-Associated Pneumonia

  • J. Solé-Violán
  • F. Rodríguez de Castro
Part of the Perspectives on Critical Care Infectious Diseases book series (CCID, volume 4)


Ventilator-associated pneumonia (VAP), is the most common infection documented in the Intensive Care Unit (ICU), with reported incidence rates of 10-30% depending on the type of ICU, the severity of illness of the study population and the diagnostic criteria used. (1,2). Crude mortality rate has ranged from 20 to 71%, (3) and debate persists about whether it is due to the infection itself or to the severe underlying illness (4,5). Indeed, the attributable mortality of VAP is questionable in some clinical settings, such as trauma patients or episodes of infections caused by primary endogenous pathogens (6). On the other hand, current data available indicate that the episodes caused by Pseudomonas aeruginosa,Acinetobacter baumanii or methicillin-resistant Staphylococcus aureus (MRSA), cause an excess of mortality compared with the predictions made on the basis of severity-ofillness on ICU admission.(7, 8, 9)


Minimal Inhibitory Concentration Respir Crit Nosocomial Pneumonia Postantibiotic Effect Acinetobacter Baumanii 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 2001

Authors and Affiliations

  • J. Solé-Violán
    • 1
  • F. Rodríguez de Castro
    • 1
  1. 1.Hospital Universitario de Gran CanariaLas Palmas de GCSpain

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