Abstract
Upon exposure to antigen, specific CD4 T cells are activated and differentiate into cytokine-producing effector cells that ultimately determine the outcome of the immune challenge. However, the activated T cells are relatively short lived and little is known about the factors that determine the proportion that develop into long-lived memory cells. Furthermore, the behavior of memory cells upon re-encounter with antigen is poorly understood.
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Ben-Sasson, S.Z. et al. (2002). Generation and Characterization of Memory Cd4 T Cells. In: Gupta, S., Butcher, E., Paul, W. (eds) Lymphocyte Activation and Immune Regulation IX. Advances in Experimental Medicine and Biology, vol 512. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0757-4_17
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DOI: https://doi.org/10.1007/978-1-4615-0757-4_17
Publisher Name: Springer, Boston, MA
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