Plant Virus Gene Vectors: Biotechnology Applications in Agriculture and Medicine

  • Karen-Beth G. Scholthof
  • T. Erik Mirkov
  • Herman B Scholthof
Part of the Genetic Engineering: Principles and Methods book series (GEPM, volume 24)


Plant virus vectors have been developed as a result of 20 years of advances in molecular biology, which produced infectious plasmid-based clones of RNA and DNA plant viruses and viroids that could be routinely amplified in E. coli. This work built on a century of progress in virology, much of which was based on understanding the biology of Tobacco mosaic virus (TMV) (1). With the availability of the rice and Arabidopis draft genome sequences, expressed sequence tags (ESTs) and microarrays, crystal structures of many plant viruses, and public interest in non-transgenic strategies for crop improvement, the technology of plant virus gene vectors holds much promise for the coming decade (2, 3, 4). The intent of this review is to define virus-vector strategies, describe uses for improving crop health, and point out possible beneficial overlaps with veterinary and human medicine.


Virus Vector Tobacco Mosaic Virus Plant Virus Tobacco Rattle Virus Benthamiana Plant 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 2002

Authors and Affiliations

  • Karen-Beth G. Scholthof
    • 1
  • T. Erik Mirkov
    • 2
  • Herman B Scholthof
    • 1
  1. 1.Department of Plant Pathology and MicrobiologyTexas A&M UniversityCollege Station
  2. 2.Texas Agricultural Experiment StationWeslaco

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