The Tear Film and Defense Against Infection
Our research program concerns the pathogenesis of bacterial corneal infection. We are studying the early events occurring when bacteria interact with the corneal surface, since it is these events that determine whether infection ensues or if the cornea can resist disease. Our long-term goals are two-fold: (1) to understand why certain factors, such as contact lens wear or preexisting trauma/disease, promote infection, and (2) to develop new approaches for prevention and therapeutics. How our research goals relate to tear film homeostasis is the subject of this paper.
KeywordsCorneal Epithelium Sodium Hyaluronate Hypotonic Solution Rose Bengal Foreign Body Sensation
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