Abstract
Tear Breakup Time (BUT), the only clinical method of measuring tear film stability, is considered to be the primary and “first test” for the diagnosis of dry eyes. 1.2; A recommendation, by the National Eye Institute/Industry Workshop on Clinical Trials in Dry Eyes, that a test for tear stability be used as a global criterion of dry eyes substantiates the importance of the BUT measurement. 1 An unstable tear film is known to be a common denominator amongst a number of conditions causing dry eyes, ocular irritation, and contact lens intolerance. 1.3 BUT is defined as the interval following a blink to the occurrence of gaps or breaks in the tear film. Lemp et al. 4.5 described a normal tear BUT to be > 10 s. Marginal dry eyes show BUTs of 5-9 s and a BUT of <5 s is indicative of dry eye disorder.
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Higgins, D., Webb, K., Shapleigh, S., Huebner, D., Carmolli, T., Hall, B. (2002). Evaluation of the Akorn Dry Eye Test (Dettm) as a Predictor of Contact Lens Comfort. In: Sullivan, D.A., Stern, M.E., Tsubota, K., Dartt, D.A., Sullivan, R.M., Bromberg, B.B. (eds) Lacrimal Gland, Tear Film, and Dry Eye Syndromes 3. Advances in Experimental Medicine and Biology, vol 506. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0717-8_159
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DOI: https://doi.org/10.1007/978-1-4615-0717-8_159
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