Somatostatin-Like Immunoreactivity (SLIR) in Rat Harderian and Meibomian Glands and Glands of Zeis

  • Mortimer Lorber
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 506)


In many species serous lacrimal glands bind sex hormones and prolactin, have cells making immunoglobulins and growth factors, and contain nerve fibers having peptides such as VIP, NPY, and Substance P.1 Because the latter neuropeptides also occur in the sebaceous meibomian gland,2 the present study sought to determine the possible presence and cellular localization of somatostatin (SOM) in the three lipid-containing3, 4 lacrimal glands of the rat. Its existence might affect neuroendocrine-immune system interactions,5 presumably diminishing them because SOM inhibits lymphocyte proliferation.6


Acinar Cell Lacrimal Gland Biliary Epithelial Cell Accessory Signal Oncogene Research Product 
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Copyright information

© Kluwer Academic/Plenum Publishers 2002

Authors and Affiliations

  • Mortimer Lorber
    • 1
  1. 1.Department of Physiology & BiophysicsGeorgetown University School of MedicineUSA

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