Inhibitory Effects of Roquefortine on Hepatic Cytochromes P450
Roquefortine, a cyclodipeptide derived from the diketopiperazine cyclo (TrpdehydroHis), is a secondary metabolite produced by some Penicillium species (1,2). P. roqueforti is considered as one of the most important fungal contaminants of carbonated beverages, beer, wine, meats, cheese, bread. It is reported to be among the predominant species in silage.
KeywordsLiver Microsome Difference Spectrum Indole Alkaloid Penicillium Species Carbonate Beverage
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