Abstract
Interesting things happen in solution. Proteins fold into their native, active conformations. Enzyme substrates bind to the proteins that operate on them, and drug molecules bind to their targets. Much of the chemical industry works with solutions in both manufacture and separation. Understanding - and hence tailoring - these processes depends on a detailed understanding of the structures in solution, and how they change as external conditions - temperature, pressure, concentration, cosolvents - are changed. Yet our understanding of structures in solution remains poor.
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Finney, J.L., Bowron, D.T. (2002). Experimental Determination of the Structures of Complex Liquids: Beyond the PDF. In: Billinge, S.J.L., Thorpe, M.F. (eds) From Semiconductors to Proteins: Beyond the Average Structure. Fundamental Materials Research. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0613-3_13
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DOI: https://doi.org/10.1007/978-1-4615-0613-3_13
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