The primary goals of therapy are control of the spasms and normalization or improvement of developmental status. This chapter is concerned primarily with initial seizure control, while the effects on long-term outcome are considered in Chapter 12. Although the management of many epileptic syndromes is difficult, infantile spasms presents a number of unique problems that have prevented the establishment of widely accepted standard treatment protocols. It is crucial that the physician be fully aware of these problems, and, in particular, be cognizant of their impact upon the interpretation of prior studies of treatment efficacy as well as their influence on determination of optimal response in individual cases.
KeywordsPositron Emission Tomography Tuberous Sclerosis Seizure Control Spontaneous Remission Infantile Spasm
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