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Cytokines and Neuropeptides

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Cytokines and Mental Health

Part of the book series: Neurobiological Foundation of Aberrant Behaviors ((NFAB,volume 7))

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Abstract

Clinical experience shows that cytokines have side effects of a central nervous system origin. Flu-like systems (fever, chills, headache, fatigue) develop rapidly with cytokine therapy. The latter symptoms are followed by neuroasthenia or fatigue syndrome (asthenia, malaise, lethargy, somnolence, headache, low-grade fevers, and Anorexia). Psychomotor, cognitive, and psychiatric changes are also observed (1–4). Numerous groups have considered the effects of cytokines on the central nervous system (5).

This work was co-author by Dr. A.J. Murgo in his private capacity. No official support or endorsement by the NCI is intended or should be inferred.

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Author information

Authors and Affiliations

  1. College of Pharmacy, University of Illinois, Chicago, Illinois, USA

    Nicholas P. Plotnikoff

  2. Center for Comprehensive Medicine, Baylor College of Medicine, Houston, Texas, USA

    Robert E. Faith

  3. National Cancer Institute, Rockville, Maryland, USA

    Anthony J. Murgo

Authors
  1. Nicholas P. Plotnikoff
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  2. Robert E. Faith
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  3. Anthony J. Murgo
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Editor information

Editors and Affiliations

  1. University of Michigan Health System, Ann Arbor, USA

    Ziad Kronfol

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Plotnikoff, N.P., Faith, R.E., Murgo, A.J. (2003). Cytokines and Neuropeptides. In: Kronfol, Z. (eds) Cytokines and Mental Health. Neurobiological Foundation of Aberrant Behaviors, vol 7. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0323-1_6

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  • DOI: https://doi.org/10.1007/978-1-4615-0323-1_6

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5020-0

  • Online ISBN: 978-1-4615-0323-1

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