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Function of PACAP in the Respiratory System

  • J. C. Prieto
Part of the Endocrine Updates book series (ENDO, volume 20)

Abstract

Since the discovery of the activity of vasoactive intestinal peptide (VIP) as a vasodilator peptide in the lung (Said, 1967) and its subsequent isolation from the small intestine (Said and Mutt, 1970), a rich array of studies has characterized the presence and/or the regulatory role of many other neuropeptides in the respiratory system (Boonsma and Said, 1992; Said, 1995; Maggi et al, 1995; Van der Velden et al, 1999). The observation of the potent anti-asthma and anti-inflammatory effects of VIP in the lung and airways was confirmed with other VIP-related peptides that possess common mechanisms of action (Said, 1992; Maggi et al, 1995).

Keywords

Vasoactive Intestinal Peptide Airway Smooth Muscle Vasoactive Intestinal Polypeptide Pituitary Adenylate Cyclase Activate Polypeptide Small Cell Lung Cancer Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Springer Science+Business Media New York 2003

Authors and Affiliations

  • J. C. Prieto
    • 1
  1. 1.University of AlcaláCampus UniversitarioAlcalá de HenaresSpain

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