Sleep pp 61-70 | Cite as

Models of human sleep regulation

  • D. G. M. Beersma


One of the reasons to assume that sleep serves important functions to an organism is the fact that timing and duration of sleep are strictly regulated. Specific rebounds occur both upon non-REM sleep deprivation as well as upon REM sleep deprivation, suggesting that the states constitute necessary physiological processes. It is, however, not yet clear what these necessary processes are. The physiological characteristics of non-REM sleep and REM sleep are very different. Apart from the absence or presence of rapid eye movements, there are differences in the electroencephalogram, in thermoregulation, in cardiovascular processes, in breathing. Virtually every physiological process is involved. Each of the processes seems to be crucial for the functioning of the organism, and so each of them may provide the ultimate reason for the rebound responses which occur upon non-REM and REM sleep deprivation.


Sleep Deprivation Circadian Pacemaker Circadian Phase Sleep Regulation Human Sleep 
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© Springer Science+Business Media New York 2003

Authors and Affiliations

  • D. G. M. Beersma
    • 1
  1. 1.Zoological LaboratoryRUGAA HarenThe Netherlands

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