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Sleep pp 577-579 | Cite as

Central alveolar hypoventilation syndrome

  • E. Weitzenblum

Abstract

Alveolar hypoventilation of central origin and primary in appearance was described over 30 years ago: it is characterised by considerable daytime hypoxemia-hypercapnia, but which is often well-tolerated, and by the abolition of the ventilatory response to a hypercapnic stimulus. Central chemoreceptor dysfunctioning, demonstrated by an abnormal response to the CO2 stimulus, is the most characteristic trait of this syndrome [2], but peripheral chemoreceptor deficiency, responsible for the ventilatory response to hypoxia, has also been observed in some cases. The syndromes of central alveolar hypoventilation and central apnoeas are not absolutely synonymous, even if the former can elicit the latter: central apnoeas have been observed in the absence of any daytime hypoventilation, and central hypoventilation syndrome is not necessarily accompanied by central apnoeas during sleep. Nor is central alveolar hypoventilation synonymous with obesity-hypoventilation syndrome (the current term for Pickwick’s syndrome) even though these conditions have several points in common. Central apnoea syndrome and obesity-hypoventilation syndrome are described in other chapters of the present volume.

Keywords

Continuous Positive Airway Pressure Ventilatory Response Nasal Continuous Positive Airway Pressure Central Apnoea Obstructive Apnoea 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer Science+Business Media New York 2003

Authors and Affiliations

  • E. Weitzenblum
    • 1
  1. 1.Service de PneumologieHôpital de HautepierreStrasbourgFrance

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