Abstract
Taurine, the second most abundant amino acid in the CNS, is acknowledged to be important in cell volume regulation yet little is known about how aging might alter taurine homeostasis. Unfortunately, few investigators have focused on the study of taurine in aging and senescence. Previously we summarized much of the older work showing that taurine content declines in a number of tissues with advanced age in rodents1. I will briefly summarize some recent studies that have examined the effects of aging on taurine. I will also summarize our own findings that point to several potential mechanisms that may impact taurine homeostasis with advanced aging.
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Dawson, R. (2003). Taurine in Aging and Models of Neurodegeneration. In: Lombardini, J.B., Schaffer, S.W., Azuma, J. (eds) Taurine 5. Advances in Experimental Medicine and Biology, vol 526. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0077-3_64
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DOI: https://doi.org/10.1007/978-1-4615-0077-3_64
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