Tropical Diseases pp 211-217 | Cite as
Molecular Diversity of Hepatitis C Virus in the Batam Region
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Abstract
The hepatitis C virus belongs to the group of the flaviviruses. The genome consists of a single strand of (+)-RNA with a length of approximately 9.5 kB. This RNA is packed into a core and an envelope that consist of lipids and core-and envelope-proteins of the virus. The RNA encodes for a large polypeptide. After translation, the polypeptide is spliced into at least 3 structural and 6 non-structural proteins. The structural proteins are the core and two envelope-proteins. Non-structural proteins are: proteases, a helicase and RNA-dependent RNA polymerase.
Keywords
Sustained Virologic Response Sustained Virologic Response Rate Visible Genetic Spontaneous Recovery Rate Serotyping Assay
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© Springer Science+Business Media New York 2003