Periodontitis and Oxidative Stress: Human Studies

  • Luigi Nibali
  • Brian Henderson
  • Giovanni Li Volti
  • Nikos Donos
Part of the Oxidative Stress in Applied Basic Research and Clinical Practice book series (OXISTRESS)


The knowledge of the pathogenic effects of oxidative stress in the periodontium, discussed in previous chapters, has stimulated several lines of research into the associations between redox status and periodontitis. Human studies in this topic range from epidemiological to treatment studies. This chapter will discuss the poorly researched topic of redox proteins in periodontal diseases and will review the association between measures of oxidative stress and presence of periodontitis. Particular emphasis will be placed on the potential role of periodontal disease pathogenic factors to determine both local and systemic oxidative stress fingerprints, measured as damage to lipids, proteins, or DNA.


High Performance Liquid Chromatography Telomere Length Ferric Reduce Antioxidant Power Chronic Periodontitis Gingival Crevicular Fluid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  1. 1.Periodontology Unit and Department of Clinical ResearchUniversity College London (UCL) Eastman Dental Institute and HospitalLondonUK
  2. 2.Division of Microbial DiseasesUCL Eastman Dental InstituteLondonUK
  3. 3.Department of Drug Sciences, Section of BiochemistryUniversity of CataniaCataniaItaly

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