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Impact of Sleep and Sleep Disturbances on Obesity and Cancer pp 155–167Cite as

Sleep Disorders and Cancer Risk

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Part of the book series: Energy Balance and Cancer ((EBAC,volume 8))

Abstract

Sleep disturbance is emerging as a novel risk factor for cancer and a number of other chronic diseases. Disruption of circadian rhythm with resultant perturbed homeostasis is believed to drive sleep disturbance-associated tumorigenesis. Much of the supporting evidence comes from studies of shift work and, more recently, short duration of sleep with risks of various types of cancer and precancerous lesions. Less is known about the relationship of other sleep disorders, which encompass a number of conditions that broadly affect sleep health, with cancer. This chapter reviews current knowledge of the association between common sleep disorders and cancer and briefly discusses the molecular mechanisms underlying the link between sleep disturbance and cancer. Effective intervention on sleep health can potentially be a new avenue for reducing cancer risk and enhancing survival.

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Authors and Affiliations

  1. Departments of Family Medicine and Community Health, Epidemiology and Biostatistics, Case Comprehensive Cancer Center, Case Western Reserve University, 11000 Cedar Avenue, Suite 402, Cleveland, OH, 44106-7136, USA

    Cheryl L. Thompson Ph.D. & Li Li M.D., Ph.D.

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  1. Cheryl L. Thompson Ph.D.
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  2. Li Li M.D., Ph.D.
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Correspondence to Cheryl L. Thompson Ph.D. .

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Editors and Affiliations

  1. Department of Medicine, Harvard Medical School Brigham and Women's Hospital, Boston, Massachusetts, USA

    Susan Redline

  2. Center for Science, Health & Society, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA

    Nathan A. Berger

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Thompson, C.L., Li, L. (2014). Sleep Disorders and Cancer Risk. In: Redline, S., Berger, N. (eds) Impact of Sleep and Sleep Disturbances on Obesity and Cancer. Energy Balance and Cancer, vol 8. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-9527-7_8

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