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Future Directions in Genetics of Psychiatric Disorders

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Behavior Genetics of Psychopathology

Part of the book series: Advances in Behavior Genetics ((AIBG,volume 2))

Abstract

From the view of statistical genetics, we explore four future directions in the genetics of psychiatric disorders with the overall goal of application to genomic medicine. The themes are (1) defining genomic variation, (2) response to treatment genomics, (3) genetic risk prediction and (4) data collection for individuals measured for phenotype, genotype and environment. We conclude that genotyping technology is no longer a limiting step and that full progression of applications of genomic medicine in psychiatry is dependent on the availability of suitable individual level data and will ultimately depend on integration of genomic information as part of accessible electronic health records.

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Acknowledgements

This work was funded by grants from the Australian Research Council (FT0911360) and the Australian National Health and Medical Research Council (613608, 1011506).

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Authors and Affiliations

  1. The University of Queensland, Queensland Brain Institute, Brisbane, QLD, 4067, Australia

    Naomi R. Wray, Enda M. Byrne, Sven Stringer & Bryan J. Mowry

  2. Academic Medical Center, Amsterdam, The Netherlands

    Sven Stringer

  3. University Medical Center Utrecht, Utrecht, The Netherlands

    Sven Stringer

  4. Queensland Centre for Mental Health Research, Brisbane, QLD, 4076, Australia

    Bryan J. Mowry

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  1. Naomi R. Wray
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  2. Enda M. Byrne
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  3. Sven Stringer
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  4. Bryan J. Mowry
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Correspondence to Naomi R. Wray .

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Editors and Affiliations

  1. Department of Psychology and NeuroScience, University of Colorado, Boulder, Colorado, USA

    Soo Hyun Rhee

  2. Department of Psychological Sciences, University of London, London, United Kingdom

    Angelica Ronald

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Wray, N.R., Byrne, E.M., Stringer, S., Mowry, B.J. (2014). Future Directions in Genetics of Psychiatric Disorders. In: Rhee, S., Ronald, A. (eds) Behavior Genetics of Psychopathology. Advances in Behavior Genetics, vol 2. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-9509-3_11

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