General Processes

  • Anthony W. H. Chan
  • Alberto Quaglia
  • Beate Haugk
  • Alastair Burt
Part of the Atlas of Anatomic Pathology book series (AAP)


The liver exhibits only a limited repertoire of morphologic changes in response to a wide variety of infectious, metabolic, immune-mediated, circulatory, or neoplastic injuries. Many such changes are neither pathognomonic nor specific and may be caused by a variety of disorders; however, recognition of the principal pattern(s) of injury is central to making a clinical diagnosis. By systematic examination and interpretation of the morphologic changes, together with correlation of clinical, biochemical, serologic, and radiologic, information, an accurate pathologic diagnosis, or at least differential diagnoses, normally can be achieved.


Intranuclear Inclusion Neoplastic Change Lobular Inflammation Macrovesicular Steatosis Ductular Reaction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • Anthony W. H. Chan
    • 1
  • Alberto Quaglia
    • 2
  • Beate Haugk
    • 3
  • Alastair Burt
    • 4
  1. 1.Prince of Wales HospitalThe Chinese University of Hong KongHong KongChina
  2. 2.Institute of Liver StudiesKing’s College HospitalLondonUK
  3. 3.Department of Cellular PathologyRoyal Victoria InfirmaryNewcastle upon TyneUK
  4. 4.School of MedicineThe University of AdelaideAdelaideAustralia

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