Recurrent Rectal Cancer

  • Todd D. Francone
  • Martin R. WeiserEmail author


Following resection of a primary rectal cancer, tumor will recur within the pelvis at a rate of 4–33 %. Because uncontrolled pelvic recurrence can lead to disabling pain, bleeding, obstruction, infection, and mortality, an aggressive surgical approach should be considered when it can be performed with acceptable morbidity and mortality. Accurate assessment of resectability is critical, as obtaining negative surgical margins is the most significant prognostic factor for long-term survival. However, reoperative pelvic surgery is challenging, as the planes of dissection are disrupted and often infiltrated by tumor. Preoperative therapy, including chemotherapy and radiation, should be employed when possible to maximize tumor shrinkage and optimize complete resection. In this chapter, we discuss the diagnosis, evaluation, and multimodality management of locally recurrent rectal cancer and the associated outcomes.


Rectal Cancer Negative Margin Parastomal Hernia Pelvic Recurrence Fecal Diversion 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  1. 1.Division of Surgery, Department of Colon and Rectal SurgeryLahey ClinicBurlingtonUSA
  2. 2.Department of SurgeryMemorial Sloan-Kettering Cancer CenterNew YorkUSA

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