Abstract
Although total mesorectal excision (TME) and abdominoperineal resection (APR) are routinely employed for major oncologic resection of more advanced rectal lesions, the transanal approach to rectal cancer is uniquely poised to provide a curative option without the added morbidity of a transabdominal procedure. Additionally, a transanal option can help preserve function without compromising oncologic outcome. Since its first description in 1966, transanal excision continues to be an ideal option in select patients who present with early tumors and favorable characteristics, as well as a palliative procedure for more advanced disease in high-risk patients. In this chapter, we will describe the outcomes associated with various transanal excisional techniques, including transanal endoscopic microsurgery (TEM) and the more recently described transanal minimally invasive surgery (TAMIS) technique, to provide recommendations regarding options for managing these lesions.
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References
Miles WE. A method of performing abdomino-perineal excision for carcinoma of the rectum and of the terminal portion of the pelvic colon. CA Cancer J Clin. 1908;21:361–4.
Marks G, Mohiuddin M, Borenstein B. Preoperative radiation therapy and sphincter preservation by the combined abdominotranssacral technique in selected rectal cancers. Dis Colon Rectum. 1985;28(8):565.
Buess G, Kipfmuller K, Hack D, et al. Technique of transanal endoscopic microsurgery. Surg Endosc. 1988;2(2):71–5.
Atallah S, Albert M, Larach S. Transanal minimally invasive surgery: a giant leap forward. Surg Endosc. 2010;24(9):2200–5.
Saclarides T. Transanal endoscopic microsurgery: a single surgeon’s experience. Arch Surg. 1998;133(6):595–9.
Kikuchi R, Takano M, Takagi K, et al. Management of early invasive colorectal cancer. Dis Colon Rectum. 1995;38(12):1286–95.
Wibe A, Syse A, Andersen E, et al. Oncological outcomes after total mesorectal excision for cure for cancer of the lower rectum: anterior vs. abdominoperineal resection. Dis Colon Rectum. 2004;47(1):48–58.
Sitzler PJ, Seow-Choen F, Ho YH, et al. Lymph node involvement and tumor depth in rectal cancers: an analysis of 805 patients. Dis Colon Rectum. 1997;40:1472–6.
Brodsky JT, Richard GK, Cohen AM, et al. Variables correlated with the risk of lymph node metastasis in early rectal cancer. Cancer. 1992;69:322–6.
Killingback M. Local excision of carcinoma of the rectum: indications. World J Surg. 1992;16:437–46.
Blumberg D, Paty P, Guillem J, et al. All patients with small intramural rectal cancers are at risk for lymph node metastasis. Dis Colon Rectum. 1999;42:881–5.
Brown G, Radcliffe A, Newcombe R, et al. Preoperative assessment of prognostic factors in rectal cancer using high-resolution magnetic resonance imaging. Br J Surg. 2003;90:355–64.
Kim HJ, Wong WD. Role of endorectal ultrasound in the conservative management of rectal cancers. Semin Surg Oncol. 2000;19:358–66.
Fidler IJ. Critical factors in the biology of human cancer metastasis: twenty-eighth G.H.A. Clowes memorial award lecture. Cancer Res. 1990;50:6130–8.
Bleday R, Breen E, Jessup JM, et al. Prospective evaluation of local excision for small rectal cancers. Dis Colon Rectum. 1997;40:388–92.
Steele GD, Herndon JE, Bleday R, et al. Sphincter-sparing treatment for distal rectal adenocarcinoma. Ann Surg Oncol. 1999;6:433–41.
Mellgren A, Sirivongs P, Rothenberger A, et al. Is local excision adequate therapy for early rectal cancer? Dis Colon Rectum. 2000;43(8):1064–71.
Mellgren A, Goldberg J, Rothenberger D. Local excision – some reality testing. Surg Oncol Clin N Am. 2005;14(2):183–96.
Madbouly K, Remzi F, Erkek B, et al. Recurrence after transanal excision of T1 rectal cancer: should we be concerned? Dis Colon Rectum. 2005;48(4):711–21.
Endreseth B, Myrvold H, Romundstad P, et al. Transanal excision vs. major surgery for T1 rectal cancer. Dis Colon Rectum. 2005;48(7):1380–8.
Saclarides T, Floyd N. Transanal endoscopic microsurgical resection of T1 rectal tumors. Dis Colon Rectum. 2006;42(2):165.
Moore JS, Cataldo PA, Osler T, Hyman NH. Transanal endoscopic microsurgery is more effective than traditional transanal excision for resection of rectal masses. Dis Colon Rectum. 2008;51:1026–30.
Atallah S, Larach S, Albert M. Transanal minimally invasive surgery: a giant leap forward. Surg Endosc. 2009;24(9):2200–5.
Albert MR, Atallah SB, deBeche-Adams TC, Izfar S, Larach SW. Transanal minimally invasive surgery (TAMIS) for local excision of benign neoplasms and early-stage rectal cancer: efficacy and outcomes in the first 50 patients. Dis Colon Rectum. 2013;56(3):301–7.
Albert M, Atallah S, Larach S, deBeche-Adams T. Minimally invasive anorectal surgery: from Parks local excision to transanal endoscopic microsurgery to transanal minimally invasive surgery. Semin Colorectal Surg. 2013;24(1):42–9.
Sebag-Montefiore D, Stephens R, Steele R, et al. Preoperative radiotherapy versus selective postoperative chemoradiotherapy in patients with rectal cancer (MRC CR07 and NCIC-CTG C016): a multicenter, randomised trial. Lancet. 2009;373(9666):811–20.
Marks G, Mohiuddin M, Masoni L, et al. High-dose preoperative radiation and full-thickness local excision. Dis Colon Rectum. 1990;33(9):735–9.
Mohiuddin M, Marks G, Bannon J. High-dose preoperative radiation and full thickness local excision: a new option for selected T3 distal rectal cancers. Int J Radiat Oncol. 1994;30(4):845–9.
Annamaneni R, Marks J, Hamdan W, Curran T, Mohiuddin M, Marks G. Full thickness local excision of prospectively staged T2 rectal cancers after neoadjuvant radiation/chemoradiation. Poster presented at: Society of Surgical Oncology annual cancer symposium; Atlanta, GA: 2005.
Mizrahi B, Marks J, Marks G, et al. T2 rectal cancer: a comparison of radical surgery and local excision by transanal endoscopic microsurgery following neoadjuvant therapy. Poster presented at: American Society of Colon & Rectal Surgeons annual scientific meeting; Hollywood, FL: 2009.
Lezoche E, Guerrieri M, Paganini A, et al. Long-term results in patients with T2-3 N0 distal rectal cancer undergoing radiotherapy before transanal endoscopic microsurgery. Br J Surg. 2005;92(12):1546–52.
Doornebosch P, Ferenschild F, de Wilt J, et al. Treatment of recurrence after transanal endoscopic microsurgery (TEM) for T1 rectal cancer. Dis Colon Rectum. 2010;53(9):1234–9.
Tsai B, Finne C, Nordenstam J, et al. Transanal endoscopic microsurgery resection of rectal tumors: outcomes and recommendation. Dis Colon Rectum. 2010;53(1):16–23.
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Transanal endoscopic microsurgery (TEM) excision of a rectal mass (Video by Peter Cataldo, MD) (MOV 187521 kb)
Transanal minimally invasive surgery removal of a rectal mass (Video by Matthew Albert, MD) (WMV 84531 kb)
Transanal minimally invasive surgery removal of a rectal mass (Video by Matthew Albert, MD) (WMV 86612 kb)
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Marks, J.H., Reynolds, H. (2014). Local Treatment of Rectal Cancer (TEM Versus TAMIS Versus Transanal Excision). In: Steele, S.R., Maykel, J.A., Champagne, B.J., Orangio, G.R. (eds) Complexities in Colorectal Surgery. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-9022-7_14
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DOI: https://doi.org/10.1007/978-1-4614-9022-7_14
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