Radiology of the Liver in Children

  • Nghia “Jack” Vo
  • Narendra Shet


Imaging can play an integral role in the evaluation, diagnosis, and even treatment of children with new or chronic hepatobiliary disorders involving a native or transplanted liver. The primary imaging modalities that are routinely called upon to evaluate the pediatric liver include ultrasound (US), computed tomography (CT), magnetic resonance imaging (MRI), and nuclear scintigraphy. The detailed anatomical capabilities offered by US, CT, and MRI have essentially eliminated the need for conventional x-ray images.


Portal Vein Portal Hypertension Transjugular Intrahepatic Portal Systemic Shunt Biliary Atresia Focal Nodular Hyperplasia 
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  1. 1.
    Williams C, Frush D. Compendium of national guidelines for imaging of the pediatric patient. Pediatr Radiol. 2012;42:82–94.PubMedCrossRefGoogle Scholar
  2. 2.
    Brenner D, Hall E. Computed tomography – an increasing source of radiation exposure. NEJM. 2007;357:2277–84.PubMedCrossRefGoogle Scholar
  3. 3.
    Strauss K, Goske M, Kaste S, et al. Image gently: ten steps you can take to optimize image quality and lower CT dose for pediatric patients. AJR Am J Roentgenol. 2010;194:868–73.PubMedCrossRefGoogle Scholar
  4. 4.
    Borders H, Barnes C, Parks D, et al. Use of a dedicated pediatric CT imaging service associated with decreased patient radiation dose. J Am Coll Radiol. 2012;9:340–3.PubMedCrossRefGoogle Scholar
  5. 5.
    Vasanawal S. MRI of the liver – how to do it. Pediatr Radiol. 2010;40:431–7.CrossRefGoogle Scholar
  6. 6.
    Chung E, Cube R, Lewis R, et al. Pediatric liver masses: radiologic-pathologic correlation part 1. Benign tumors. Radiographics. 2010;30:801–26.PubMedCrossRefGoogle Scholar
  7. 7.
    Stocker J. Hepatic tumors in children. Clin Liver Dis. 2001;5(1):259–81.PubMedCrossRefGoogle Scholar
  8. 8.
    Ishak K, Goodman Z, Stocker J. Tumors of the liver and intrahepatic bile ducts. Washington, DC: Armed Forces Institute of Pathology; 2001.Google Scholar
  9. 9.
    Roebuck D. Assessment of malignant liver tumors in children. Cancer Imaging. 2009;9:S98–103.PubMedCrossRefPubMedCentralGoogle Scholar
  10. 10.
    Chung E, Lattin G, Cube R, et al. Pediatric liver masses: radiologic-pathologic correlation part 2. Malignant tumors. Radiographics. 2011;31:483–507.PubMedCrossRefGoogle Scholar
  11. 11.
    Llovet J, Real M, Montana X, et al. Arterial embolization or chemoembolization versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomized controlled trial. Lancet. 2002;359:1734–9.PubMedCrossRefGoogle Scholar
  12. 12.
    Malogolowkin M, Stanley P, Steele D, et al. Feasibility and toxicity of chemoembolization for children with liver tumors. J Clin Oncol. 2000;18:1279–84.PubMedGoogle Scholar
  13. 13.
    Lee MS, Kim M, Lee MJ, et al. Biliary atresia: color Doppler US findings in neonates and infants. Radiology. 2009;252(1):282–9.PubMedCrossRefGoogle Scholar
  14. 14.
    Park W, Choi S, Lee H. The ultrasonographic “triangular cord” coupled with gallbladder images in the diagnostic prediction of biliary atresia from infantile intrahepatic cholestasis. J Pediatr Surg. 1999;34:1706–10.PubMedCrossRefGoogle Scholar
  15. 15.
    Mittal V, Saxena A, Sodhi K, et al. Role of abdominal sonography in the preoperative diagnosis of extrahepatic biliary atresia in infants younger than 90 days. AJR Am J Roentgenol. 2011;196:W438–45.PubMedCrossRefGoogle Scholar
  16. 16.
    Kim O, Chung H, Choi B. Imaging of the choledochal cyst. Radiographics. 1995;15:69–88.PubMedCrossRefGoogle Scholar
  17. 17.
    Tchelepi H, Ralls P, Radin R, Grant E. Sonography of diffuse liver disease. J Ultrasound Med. 2002;21(9):1023–32.PubMedGoogle Scholar
  18. 18.
    Giorgio F, Amoroso P, Fico P, et al. Ultrasound evaluation of uncomplicated and complicated acute viral hepatitis. J Clin Ultrasound. 1986;14(9):675–769.PubMedCrossRefGoogle Scholar
  19. 19.
    Pariente D, Franchi-Abella S. Paediatric chronic liver diseases: how to investigate and follow up? Role of imaging in the diagnosis of fibrosis. Pediatr Radiol. 2010;40:906–19.PubMedCrossRefGoogle Scholar
  20. 20.
    Vo N, Shivaram G, Andrews R, et al. Midterm follow-up of transjugular intrahepatic portosystemic shunts using polytetrafluoroethylene endografts in children. J Vasc Interv Radiol. 2012;23(7):919–24.PubMedCrossRefGoogle Scholar
  21. 21.
    Bambini D, Superina R, Almond P, et al. Experience with the Rex shunt (mesenterico-left portal bypass) in children with extrahepatic portal hypertension. J Pediatr Surg. 2000;35:13–9.PubMedCrossRefGoogle Scholar
  22. 22.
    DeLeve L, Valla D, Garcia-Tsao G. Vascular disorders of the liver. Hepatology. 2009;49:1729–64.PubMedCrossRefGoogle Scholar
  23. 23.
    Singh A, Nachiappan A, Verma H, et al. Postoperative imaging in liver transplantation: what radiologists should know. Radiographics. 2010;30:339–51.PubMedCrossRefGoogle Scholar
  24. 24.
    Miraglia M, Maruzzelli M, Spada M, et al. Transjugular liver biopsy in pediatric patients with left split liver transplantation and severe coagulation impairment. Pediatr Transplant. 2012;16:58–62.PubMedCrossRefGoogle Scholar
  25. 25.
    Lencioni R, Crocetti L, Pina M, Cioni D. Percutaneous image-guided radiofrequency ablation of liver tumors. Abdom Imaging. 2009;34:547–56.PubMedCrossRefGoogle Scholar
  26. 26.
    Hall T, Garcea G, Bilku D, Dnnison A. Management of acute non-cirrhotic and non-malignant portal vein thrombosis: a systematic review. World J Surg. 2011;35(11):2510–20.PubMedCrossRefGoogle Scholar
  27. 27.
    Darcy M. Single-session treatment of portal vein thrombosis using combined pharmacomechanical thrombolysis. Seminars Interv Radiol. 2007;24(3):327–32.CrossRefGoogle Scholar
  28. 28.
    Zerem E, Hadzic A. Sonographically guided percutaneous catheter drainage versus needle aspiration in the management of pyogenic liver abscess. AJR Am J Roentgenol. 2007;189(3):W138–42.PubMedCrossRefGoogle Scholar
  29. 29.
    Liu C, Gervais D, Hahn P, et al. Percutaneous hepatic abscess drainage: do multiple abscesses or multiloculated abscesses preclude drainage or affect outcome? J Vasc Interv Radiol. 2009;20(8):1059–65.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  1. 1.Division of Pediatric Radiology, Section of Pediatric Vascular and Interventional RadiologyChildren’s Hospital of Wisconsin and the Medical College of WisconsinMilwaukeeUSA
  2. 2.Department of RadiologySeattle Children’s HospitalSeattleUSA

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