Hepatic Tumors

Chapter

Abstract

Primary hepatic neoplasms are rare in childhood and their presentation is usually as a palpable mass with few if any other symptoms. Despite the asymptomatic presentation, the majority that do present in this young age group are malignant. Serum alpha-fetoprotein, although characteristically elevated in some hepatic tumors, is not elevated in all malignant liver tumors of childhood. Radiologic and histological assessments are vital for making accurate diagnoses and for guiding appropriate therapy. This chapter will review the most common of the benign and malignant primary hepatic masses that present in childhood.

Keywords

Corticosteroid Sarcoma Doxorubicin Gall Androgen 

Abbreviations

AFP

Serum alpha-fetoprotein

CT

Computed tomography

EHE

Epithelioid hemangioendothelioma

ESL

Embryonal (undifferentiated) sarcoma of the liver

FLC

Fibrolamellar carcinoma

FNH

Focal nodular hyperplasia

HA

Hepatocellular adenoma

HB

Hepatoblastoma

HCC

Hepatocellular carcinoma

HR

Hepatobiliary rhabdomyosarcoma

IHH

Infantile hepatic hemangioma

MH

Mesenchymal hamartoma

MRI

Magnetic resonance imaging

NRH

Nodular regenerative hyperplasia

RICH

Rapidly involuting congenital hemangioma

US

Ultrasound

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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • Rohit Gupta
    • 1
  • André A. Dick
    • 2
  • Karen F. Murray
    • 1
  1. 1.Division of Pediatric Gastroenterology and HepatologySeattle Children’s Hospital, University of Washington School of MedicineSeattleUSA
  2. 2.Division of Pediatric Transplantation, Department of SurgeryUniversity of Washington School of Medicine, Seattle Children’s HospitalSeattleUSA

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