Pharmacokinetics, Pharmacodynamics, and Physical Properties of Inhalational Agents

  • Hanjo Ko
  • Alan David Kaye
  • Richard D. Urman


While there are multiple inhalational agents discovered over the past few decades, only three remain particularly relevant today in the United States. This chapter will review major properties of sevoflurane, desflurane, isoflurane, nitrous oxide, and halothane in clinical practice as well as the basic pharmacodynamics and pharmacokinetics of inhalational agents.


Nitrous Oxide Malignant Hyperthermia Minimum Alveolar Concentration Inhalational Agent Barium Hydroxide 
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Supplementary material


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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  • Hanjo Ko
    • 1
  • Alan David Kaye
    • 2
    • 3
  • Richard D. Urman
    • 4
    • 5
  1. 1.Department of Anesthesiology and Perioperative MedicineBrigham and Women’s HospitalBostonUSA
  2. 2.Department of AnesthesiologyTulane Medical CenterNew OrleansUSA
  3. 3.Department of AnesthesiologyLouisiana State University Health Sciences CenterNew OrleansUSA
  4. 4.Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women’s HospitalHarvard Medical SchoolBostonUSA
  5. 5.Center for Perioperative Management and Medical InformaticsBrigham and Women’s HospitalBostonUSA

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