High Altitude pp 357-377 | Cite as

Human Evolution at High Altitude

Abstract

This chapter reviews evidence that natural selection is acting or has acted on indigenous high-altitude populations of the Andean, Tibetan and East African plateaus and resulted in distinctive biological characteristics conferring vigor and health. It describes the results of classic era and genomic era approaches to detecting natural selection. Genomic era evidence of natural selection on high-altitude populations is accumulating rapidly and broadly supports that from the classic era. An important remaining step is to associate phenotypic with genomic variation and to associate them with survival and reproduction, the demographic currency of natural selection.

Keywords

Migration Attenuation Cobalt Recombination Adenosine 

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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  1. 1.Department of AnthropologyCase Western Reserve UniversityClevelandUSA

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