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Dyslipidemia

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Endocrinology and Diabetes

Abstract

Atherosclerosis represents a complex inflammatory disease of multifactorial origin, dyslipidemia being a major modifiable risk factor for its development. Thus, the control of dyslipidemia associated with other important risk factors (smoking, diabetes, hypertension) emerges as an important way to achieve a reduction in cardiovascular risk [1–3].

We can define dyslipidemia as changes in circulating levels of lipids in relation to reference values for a determined population sample, considering an increase in total cholesterol (TC), LDL-cholesterol (LDL-C), and triglyceride (TG) above the 95th percentile or HDL-cholesterol (HDL-C) below the 10th percentile for the general population.

Studies have shown that in addition to the quantitative changes, qualitative differences between lipoproteins can have a significant influence on the clinical outcome [4, 5]. Therefore, the most important procedure in a patient with a diagnosis of dyslipidemia is to make an assessment of the risk of their presenting a cardiovascular event in the coming years, thereby establishing lipid targets, control targets that have a potential impact on mortality.

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Authors and Affiliations

  1. Universidade Federal de Campina Grande, Rua Aprígio Veloso, 882, Bairro Universitário, Campina Grande, Paraiba, 52429-140, Brazil

    Erik T. Diniz M.D.

  2. Division of Endocrinology and Diabetes, University of Pernambuco Medical School, Agamenon Magalhães Hospital, Recife, PE, Brazil

    Francisco Bandeira M.D., Ph.D.

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  1. Erik T. Diniz M.D.
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Correspondence to Erik T. Diniz M.D. .

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Editors and Affiliations

  1. Professor Associado e Livre-Docente, Disciplina de Endocrinologia da Faculdade de Ciências Medicas da Universidade de Pernambuco, Chefe da Divisão de Endocrinologia e Diabetes do Hospital Agamenon, Magalhães-MS/UPE, Recife, Brazil

    Francisco Bandeira

  2. American Thyroid Association Past President, American Association of Clinical Endocrinologists, Professor of Medicine, Mayo Clinic College of Medicine President-Elect, Rochester, Minnesota, USA

    Hossein Gharib

  3. Federal Foundation and School of Medical Sciences, Porto Alegre, Brazil

    Airton Golbert

  4. Department of Medicine, University of Pernambuco School of Medicine, Recife, Brazil

    Luiz Griz

  5. Department of Medicine, University of Maranhao School of Medicine, Sao Luis, Brazil

    Manuel Faria

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Diniz, E.T., Bandeira, F. (2014). Dyslipidemia. In: Bandeira, F., Gharib, H., Golbert, A., Griz, L., Faria, M. (eds) Endocrinology and Diabetes. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-8684-8_40

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