Sample Analysis and Data Processing

  • Michael Kinter
  • Caroline S. Kinter
Part of the SpringerBriefs in Systems Biology book series (BRIEFSBIOSYS)


The application of a selected reaction monitoring method in a complete, multiplexed assay is achieved by combining multiple descriptors. Care must be taken to find an optimal number of targets so that proper sampling of the chromatographic experiment is still obtained. The final challenge is then analyzing the data to determine the signals for the respective peptides and calculating an amount of each protein. Internal standards and housekeeping proteins facilitate this process.


Chromatographic Peak Select Reaction Monitoring Fragmentation Reaction Quantitative Proteomics Mass Spectrometry Experiment 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Michael Kinter
    • 1
  • Caroline S. Kinter
    • 1
  1. 1.Oklahoma Medical Research FoundationOklahoma CityUSA

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