Skip to main content

Noninvasive Hemoglobin Monitoring

  • Chapter
  • First Online:

Abstract

Noninvasive hemoglobin measurement devices are becoming commercially available and have the potential to offer many health care benefits. Current technologies utilize multiple-wavelength spectrophotometry, occlusion spectroscopy, and transcutaneous reflection spectroscopy to estimate hemoglobin noninvasively. Market availability, ease of use, agreement to invasive methods of hemoglobin measurement, and ability to provide continuous or spot check measurements differ by device. Here, we review the clinical evidence on accuracy and clinical utility of four types of noninvasive hemoglobin measurement technologies.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   79.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   99.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

References

  1. Macknet MR, Allard M, Applegate 2nd RL, Rook J. The accuracy of noninvasive and continuous total hemoglobin measurement by pulse CO-Oximetry in human subjects undergoing hemodilution. Anesth Analg. 2010;111(6):1424–6.

    Article  PubMed  Google Scholar 

  2. Gomez-Simon A, Navarro-Nunez L, Perez-Ceballos E, Lozano ML, Candela MJ, Cascales A, et al. Evaluation of four rapid methods for hemoglobin screening of whole blood donors in mobile collection settings. Transfus Apher Sci. 2007;36(3):235–42.

    Article  PubMed  Google Scholar 

  3. Van de Louw A, Lasserre N, Drouhin F, Thierry S, Lecuyer L, Caen D, et al. Reliability of HemoCue in patients with gastrointestinal bleeding. Intensive Care Med. 2007;33(2):355–8.

    Article  PubMed  Google Scholar 

  4. Mimoz O, Frasca D, Medard A, Soubiron L, Debaene B, Dahyot-Fizelier C. Reliability of the HemoCue(R) hemoglobinometer in critically ill patients: a prospective observational study. Minerva Anestesiol. 2011;77(10):979–85.

    PubMed  CAS  Google Scholar 

  5. Frasca D, Dahyot-Fizelier C, Catherine K, Levrat Q, Debaene B, Mimoz O. Accuracy of a continuous noninvasive hemoglobin monitor in intensive care unit patients. Crit Care Med. 2011;39(10):2277–82.

    Article  PubMed  Google Scholar 

  6. Miller RD, Ward TA, Shiboski SC, Cohen NH. A comparison of three methods of hemoglobin monitoring in patients undergoing spine surgery. Anesth Analg. 2011;112(4):858–63.

    Article  PubMed  CAS  Google Scholar 

  7. Berkow L, Rotolo S, Mirski E. Continuous noninvasive hemoglobin monitoring during complex spine surgery. Anesth Analg. 2011;113(6):1396–402.

    Article  PubMed  CAS  Google Scholar 

  8. Colquhoun DA, Forkin KT, Durieux ME, Thiele RH. Ability of the Masimo pulse CO-Oximetry to detect changes in hemoglobin. J Clin Monit Comput. 2012;26(2):69–73.

    Article  PubMed  Google Scholar 

  9. Lamhaut L, Apriotesei R, Combes X, Lejay M, Carli P, Vivien B. Comparison of the accuracy of noninvasive hemoglobin monitoring by spectrophotometry (SpHb) and HemoCue(R) with automated laboratory hemoglobin measurement. Anesthesiology. 2011;115(3):548–54.

    Article  PubMed  CAS  Google Scholar 

  10. Vos JJ, Kalmar AF, Struys MMRF, Porte RJ, Wietasch JK, Scheeren TW, et al. Accuracy of non-invasive measurement of haemoglobin concentration by pulse co-oximetry during steady-state and dynamic conditions in liver surgery. Br J Anaesth. 2012;109(4):522–8.

    Article  PubMed  CAS  Google Scholar 

  11. Isosu T, Obara S, Hosono A, Ohashi S, Nakano Y, Imaizumi T, et al. Validation of continuous and noninvasive hemoglobin monitoring by pulse CO-oximetry in Japanese surgical patients. J Clin Monit Comput. 2013;27(1):55–60.

    Article  PubMed  Google Scholar 

  12. Nguyen BV, Vincent JL, Nowak E, Coat M, Paleiron N, Gouny P, et al. The accuracy of noninvasive hemoglobin measurement by multiwavelength pulse oximetry after cardiac surgery. Anesth Analg. 2011;113(5):1052–7.

    Article  PubMed  CAS  Google Scholar 

  13. Causey MW, Miller S, Foster A, Beekley A, Zenger D, Martin M. Validation of noninvasive hemoglobin measurements using the Masimo Radical-7 SpHb Station. Am J Surg. 2011;201(5):590–6.

    Article  Google Scholar 

  14. Butwick A, Hilton G, Carvalho B. Non-invasive haemoglobin measurement in patients undergoing elective caesarean section. Br J Anaesth. 2012;108(2):271–7.

    Article  PubMed  CAS  Google Scholar 

  15. Skelton VA, Wijayasinghe N, Sharafudeen S, Sange A, Parry NS, Junghans C. Evaluation of point-of-care haemoglobin measuring devices: a comparison of Radical-7 pulse co-oximetry, HemoCue((R)) and laboratory haemoglobin measurements in obstetric patients*. Anaesthesia. 2013;68(1):40–5.

    Article  PubMed  CAS  Google Scholar 

  16. Coquin J, Dewitte A, Le Manach Y, Caujolle M, Joannes-Boyau O, Fleureau C, et al. Precision of noninvasive hemoglobin-level measurement by pulse co-oximetry in patients admitted to intensive care units for severe gastrointestinal bleeds. Crit Care Med. 2012;40(9):2576–82.

    Article  PubMed  CAS  Google Scholar 

  17. Chung JWMD, Park JSMD, Kim AJMD, et al. Non-invasive hemoglobin measurement in emergency patients. Korean J. 2010;21(1):6.

    Google Scholar 

  18. Gayat E, Aulagnier J, Matthieu E, Boisson M, Fischler M. Non-invasive measurement of hemoglobin: assessment of two different point-of-care technologies. PLoS One. 2012;7(1):e30065.

    Article  PubMed  CAS  Google Scholar 

  19. Gayat E, Bodin A, Sportiello C, Boisson M, Dreyfus JF, Mathieu E, et al. Performance evaluation of a noninvasive hemoglobin monitoring device. Ann Emerg Med. 2011;57(4):330–3.

    Article  PubMed  Google Scholar 

  20. Crowley C, Montenegro-Bethancourt G, Arriaga C, Solomons N, Schumann K. Correspondence of hemoglobin values obtained by a noninvasive, cutaneous-contact method with values obtained by conventional methods from whole blood samples in a Guatemalan field setting. Food Nutr Bull. 2010;31:503–12.

    Google Scholar 

  21. Crowley C, Montenegro-Bethancourt G, Solomons NW, Schumann K. Validity and correspondence of non-invasively determined hemoglobin concentrations by two trans-cutaneous digital measuring devices. Asia Pac J Clin Nutr. 2012;21(2):191–200.

    PubMed  CAS  Google Scholar 

  22. Ehrenfeld JM, Henneman JP. Impact of continuous and noninvasive hemoglobin monitoring on intraoperative blood transfusions. In: Proceedings of the 2010 annual meeting of the American Society Anesthesiologists, San Diego; 2010: Abstract # LB05.

    Google Scholar 

  23. Hadar E, Raban O, Bouganim T, Tenenbaum-Gavish K, Hod M. Precision and accuracy of noninvasive hemoglobin measurements during pregnancy. J Matern Fetal Neonatal Med. 2012;25(12):2503–6.

    Article  PubMed  CAS  Google Scholar 

  24. Rabe H, Stupp N, Ozgun M, Harms E, Jungmann H. Measurement of transcutaneous hemoglobin concentration by noninvasive white-light spectroscopy in infants. Pediatrics. 2005;116(4):841–3.

    Article  PubMed  Google Scholar 

  25. Rabe H, Alvarez RF, Whitfield T, Lawson F, Jungmann H. Spectroscopic noninvasive measurement of hemoglobin compared with capillary and venous values in neonates. Neonatology. 2010;98(1):1–5.

    PubMed  CAS  Google Scholar 

  26. Neufeld L, Garcia-Guerra A, Sanchez-Francia D, Newton-Sanchez O, Ramirez-Villalobos MD, Rivera-Dommarco J. Hemoglobin measured by Hemocue and a reference method in venous and capillary blood: a validation study. Salud Publica Mex. 2002;44(3):219–27.

    Article  PubMed  Google Scholar 

  27. Yang ZW, Yang SH, Chen L, Qu J, Zhu J, Tang Z. Comparison of blood counts in venous, fingertip and arterial blood and their measurement variation. Clin Lab Haematol. 2001;23(3):155–9.

    Article  PubMed  CAS  Google Scholar 

  28. Gehring H, Duembgen L, Peterlein M, Hagelberg S, Dibbelt L. Hemoximetry as the “”gold standard”? Error assessment based on differences among identical blood gas analyzer devices of five manufacturers. Anesth Analg. 2007;105(6 Suppl):S24–30.

    Article  PubMed  Google Scholar 

  29. Recommendations for reference method for haemoglobinometry in human blood (ICSH standard 1986) and specifications for international haemiglobin cyanide reference preparation (3rd edition). International Committee for Standardization in Haematology; Expert Panel on Haemoglobinometry. Clin Lab Haematol. 1987;9(1):73–9.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Michael O’Reilly MD, MS .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2014 Springer Science+Business Media New York

About this chapter

Cite this chapter

Begnoche, V., O’Reilly, M. (2014). Noninvasive Hemoglobin Monitoring. In: Ehrenfeld, J., Cannesson, M. (eds) Monitoring Technologies in Acute Care Environments. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-8557-5_36

Download citation

  • DOI: https://doi.org/10.1007/978-1-4614-8557-5_36

  • Published:

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4614-8556-8

  • Online ISBN: 978-1-4614-8557-5

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics