Colorectal Cancer: Adjuvant Therapy

  • Kelli Bullard Dunn
  • Judith L. Trudel


  • The stage of disease at presentation is the most important predictor of outcome for colon cancer patients. Stage I disease (T1-2N0M0) has a 5-year survival rate of 95 % after resection, and surgical treatment alone is considered sufficient.

  • Stage II disease (T3-4N0M0) has a 5-year survival, averages 70–80 %, but a subset of high-risk patients have poorer prognosis and may benefit from adjuvant therapy.

  • Stage III (TanyN1-2M0) disease has improved survival with adjuvant treatment, with 5-year survival of approximately 40–60 %.


Local Recurrence Rectal Cancer Total Mesorectal Excision Local Recurrence Rate Preoperative Radiotherapy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  1. 1.Department of SurgeryUniversity of Louisville School of MedicineLouisvilleUSA
  2. 2.Department of SurgeryUniversity of MinnesotaSt. PaulUSA

Personalised recommendations