Colorectal Cancer: Adjuvant Therapy
The stage of disease at presentation is the most important predictor of outcome for colon cancer patients. Stage I disease (T1-2N0M0) has a 5-year survival rate of 95 % after resection, and surgical treatment alone is considered sufficient.
Stage II disease (T3-4N0M0) has a 5-year survival, averages 70–80 %, but a subset of high-risk patients have poorer prognosis and may benefit from adjuvant therapy.
Stage III (TanyN1-2M0) disease has improved survival with adjuvant treatment, with 5-year survival of approximately 40–60 %.