Colorectal Cancer: Adjuvant Therapy



  • The stage of disease at presentation is the most important predictor of outcome for colon cancer patients. Stage I disease (T1-2N0M0) has a 5-year survival rate of 95 % after resection, and surgical treatment alone is considered sufficient.

  • Stage II disease (T3-4N0M0) has a 5-year survival, averages 70–80 %, but a subset of high-risk patients have poorer prognosis and may benefit from adjuvant therapy.

  • Stage III (TanyN1-2M0) disease has improved survival with adjuvant treatment, with 5-year survival of approximately 40–60 %.


Local Recurrence Rectal Cancer Total Mesorectal Excision Local Recurrence Rate Preoperative Radiotherapy 
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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  1. 1.Department of SurgeryUniversity of Louisville School of MedicineLouisvilleUSA
  2. 2.Department of SurgeryUniversity of MinnesotaSt. PaulUSA

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