Abstract
The discovery of microRNAs (miRNAs) as regulators of gene expression and of their involvement in human carcinogenesis represents one of the most important scientific discoveries of the last decade. This statement is supported by the plethora of works published in this field which reflect the broad interest of the scientific community for this topic. Recently, it has been shown that miRNAs not only modulate the expression of targeted genes but they are also involved in modulating intercellular signaling within the tumor microenvironment. Finally, new groups of noncoding RNAs are emerging as key players in carcinogenesis and a better understanding of their function and biology identifies new anticancer molecular targets.
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Acknowledgments
Dr Fabbri is supported by the Jean Perkins Foundation, by Nautica Malibu Triathlon Funds by the St. Baldrick’s Foundation, by a Southern California CTSI grant, by the Pablove Foundation, by Funds from the Saban Research Institute, by award number P30CA014089 from the National Cancer Institute, by the Hugh and Audy Lou Colvin Foundation, and by the T.J. Martell Foundation.
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Fabbri, M. (2014). Introduction. In: Fabbri, M. (eds) Non-coding RNAs and Cancer. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-8444-8_1
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DOI: https://doi.org/10.1007/978-1-4614-8444-8_1
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