Clinical, Radiologic, and Technical Considerations

  • César R. Lacruz
  • Javier Sáenz de Santamaría
  • Ricardo H. Bardales
Part of the Essentials in Cytopathology book series (EICP, volume 13)


Intraoperative cytology consultation in neuropathology is a process that must be preceded by adequate clinical and radiologic evaluation. An adequate sample requires an adequate squash/smear preparation technique, and adequate H&E or Papanicolaou and Romanowsky stains.


Posterior Fossa Pilocytic Astrocytoma Primitive Neuroectodermal Tumor Sellar Region Relevant Medical History 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Suggested Reading

  1. Boom ME, Drijver JS. Routine cytological staining techniques. London: Macmillan; 1986.Google Scholar
  2. Burger PC, Nelson JS. Stereotactic brain biopsies: specimen preparation and evaluation. Arch Pathol Lab Med. 1997;121:477–80.PubMedGoogle Scholar
  3. Burger PC, Scheithauer BW, Lee RR, O’Neill PB. An interdisciplinary approach to avoid the overtreatment of patient with central nervous system lesions. Cancer. 1997;80:2040–6.PubMedCrossRefGoogle Scholar
  4. Burger PC, Nelson JS, Boyko OB. Diagnostic synergy in radiology and surgical neuropathology: neuroimaging techniques and general interpretative guidelines. Arch Pathol Lab Med. 1998a;122:609–19.PubMedGoogle Scholar
  5. Burger PC, Nelson JS, Boyko OB. Diagnostic synergy in radiology and surgical neuropathology: radiographic findings of specific pathologic entities. Arch Pathol Lab Med. 1998b;122:620–32.PubMedGoogle Scholar
  6. Chandrasoma PT, Apuzzo MLJ. Stereotactic brain biopsy. New York: Igaku-Shoin; 1989. p. 1–63.Google Scholar
  7. Gill GH. Cytopreparation. Principles & Practice. In: Rosenthal DL, editor. Essentials in cytopathology series. New York: Springer; 2013.Google Scholar
  8. Moss TH, Nicoll JAR, Ironside JW. Intra-operative diagnosis of CNS tumours. London: Arnold; 1997.Google Scholar
  9. Seliem RM, Assaad MW, Gorombey SJ, Moral LA, Kirkwood JR, Otis CN. Fine-needle aspiration biopsy of the central nervous system performed freehand under computed tomography guidance without stereotactic instrumentation. Cancer. 2003;99:277–84.PubMedCrossRefGoogle Scholar
  10. Yachnis AT. Intraoperative consultation for nervous system lesions. Semin Diagn Pathol. 2002;19:192–206.PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • César R. Lacruz
    • 1
  • Javier Sáenz de Santamaría
    • 2
  • Ricardo H. Bardales
    • 3
  1. 1.University General Hospital Gregorio MarañónMadridSpain
  2. 2.University Hospital Extremadura Medical SchoolBadajozSpain
  3. 3.Outpatient Pathology AssociatesSacramentoUSA

Personalised recommendations