Skull Base Tumors

Abstract

Radiosurgery in the base of skull region can be especially challenging due to immediate proximity of critical structures such as brainstem and critical nerves such as those of the optic system. This chapter should guide clinicians in understanding the technical possibilities, determining feasibility, and risks of radiosurgery as well as critical organ dose limits for primary or repeat radiosurgery in this region. Specifically, radiosurgery of rare tumors of this region such as chordomas and chondrosarcomas, glomus jugulare tumors, esthesioneuroblastomas and angiofibromas are discussed according to current literature. Many of these tumors are quite amenable to radiosurgery depending upon histology, size, and location. However, ideally, modern techniques of (sometimes multimodality) imaging should be used to determine precise tumor-extent prior to the recommendation for radiosurgery, as in general, tumors larger than 3 cm or those abutting critical structures may benefit more from alternative precision therapies.

Keywords

Obesity Toxicity Neuropathy Fractionation Sarcoma 

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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  • Reinhart A. J. Sweeney
    • 1
  • Matthias Guckenberger
    • 2
  1. 1.Department of Radiation OncologyMVZ Immed, Klinik Bad TrisslOberaudorfGermany
  2. 2.Department of Radiation OncologyUniversity WürzburgWürzburgGermany

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