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Photocontact Dermatitis

  • Nicholas GulatiEmail author
  • Emma Guttman-Yassky
Chapter

Abstract

Photocontact dermatitis (PCD) belongs to the category of skin diseases known as photodermatoses, which are skin disorders caused or aggravated by ultraviolet (UV) radiation and/or visible light. PCD is divided into two categories: phototoxic and photoallergic. Phototoxic (photo-irritant) reactions are caused by direct damage to tissue resulting from light activation of the photosensitizing agent without an immunological basis. On the other hand, photoallergic reactions are cell-mediated immune responses in which the antigen is the light-activated photosensitizing agent and these reactions only occur after previous specific sensitization. PCD can be caused by either cutaneous contact or systemic uptake [1]. Chronic actinic dermatitis, a condition which is clinically similar to photodermatitis, can occur both as a sequelae of photoallergic reactions or de novo [2].

Keywords

Allergic Contact Dermatitis Cutaneous Contact Photosensitize Agent Phototoxic Reaction Photopatch Testing 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  1. 1.Laboratory for Investigative DermatologyThe Rockefeller UniversityNew YorkUSA
  2. 2.Department of DermatologyMount Sinai NYNew YorkUSA

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