Herpes Simplex Virus

  • Rachel GordonEmail author
  • Stephen Tyring


Our understanding of human herpes simplex virus (HSV) has increased tremendously since the early descriptions of disease provided by Hippocrates [1, 2]. Notable advances include the correlation of herpetic lesions with genital infections in the eighteenth century [3] and Vidal’s recognition of human-to-human transmission in 1893 [2]. Antigenic differences between HSV subtypes, suspected on clinical observations by Lipschitz [4], were confirmed in 1968 [5]. In modern day, there is successful antiviral treatment available for most HSV infections [6]. Insight into the viral life cycle and gene expression has been a driving force behind the development of antiviral treatment, including new vaccines and gene therapy [4].


Herpes Simplex Virus Genital Herpes Herpes Simplex Virus Infection Recurrent Herpes Genitalis Recurrent Herpes 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  1. 1.Department of DermatologyThe University of Texas Medical School at HoustonHoustonUSA
  2. 2.Department of DermatologyThe University of Texas at HoustonHoustonUSA

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