Benign Squamous Proliferations
There are few esophageal squamous proliferations that are not malignant. In fact, it was challenging to find enough examples for a separate chapter. The two most common are the glycogen acanthosis, a difficult lesion to classify, and the squamous papilloma, which is more likely a benign neoplasm. A few proliferations are sometimes confused with squamous carcinoma, mostly the long prong squamous proliferation at the edge and base of ulcers and squamous hyperplasia with pleomorphic nuclei (see Chap. 2). This chapter includes a spectacular, mass-forming, benign-appearing squamous proliferation that we had trouble placing in the squamous chapters. We were not exactly sure what it was, but it did not seem malignant cytologically.