Abstract
There has been significant advancement in mammographic technology since the widespread deployment of screening began in the 1970s. Utilization of screening mammography has dramatically altered the clinical presentation of breast cancer. There remains, however, a subset of breast cancer (accounting for approximately 15–20 %), which is not detectable with even modern digital 2D mammography. This is generally seen in women with radiographically dense breasts in whom mammographic sensitivity for breast cancer falls to just 50 % [Carney et al., Ann Intern Med 138:168–175, 2003]. According to a recent study in the Journal of the National Cancer Institute, these women with dense breast tissue, in whom conventional 2D mammography is limited, are actually at a higher risk for developing breast cancer [Yaghjyan et al., J Natl Cancer Inst 103(15):1179–89, 2011].
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Tabar L, Yen M, Vitak B, et al. Mammography service screening and mortality in breast cancer patients: 20-year follow-up before and after introduction of screening. Lancet. 2003;361:1405–10.
Cady B, Stone MD, Schuler JG, Thakur R, Wanner MA, Lavin PT. The new era in breast cancer: invasion, size and nodal involvement dramatically decreasing as a result of mammographic screening. Arch Surg. 1996;131:301–8.
Carney PA, Miglioretti DL, Yankaskas BC, et al. Individual and combined effects of age, breast density, and hormone replacement therapy use on the accuracy of screening mammography. Ann Intern Med. 2003;138:168–75.
Yaghjyan L et al. Mammographic breast density and subsequent risk of breast cancer in postmenopausal women according to tumor characteristics. J Natl Cancer Inst. 2011;103(15):1179–89.
Niklason LT, Christian BT, Niklason LE, et al. Digital tomosynthesis in breast imaging. Radiology. 1997;205:399–406.
Rafferty E, Niklason L. FFDM vs. FFDM with tomosynthesis for women with radiographically dense breasts: an Enriched Retrospective Reader Study. Presented at Radiological Society of North America 2011 scientific assembly and annual meeting, Chicago, IL. rsna2011.rsna.org/search/event_display.cfm?am_id=2&em_id=11016626&printmode=Y&autoprint=N.
Gur D, Bandos AI, Rockette HE, et al. Localized detection and classification of abnormalities on FFDM and tomosynthesis examinations rated under an FROC paradigm. AJR Am J Roentgenol. 2011;096:737–41.
Skaane P, Gullien R, Eben E, et al. Reading time of FFDM and tomosynthesis in a population-based screening program (abstr). Presented at Radiological Society of North America 2011 scientific assembly and annual meeting, Chicago, IL. rsna2011.rsna.org/search/event_display.cfm?am_id=2&em_id=11011027&printmode=Y&autoprint=N
Wallis MG, Moa E, Zanca F, et al. Two-view and single-view tomosynthesis versus full-field digital mammography: high resolution X-Ray Imaging Observer Study. Radiology. 2012;262(3):788–96. doi:10.1148/radiol.11103514. 103514; Published online January 24, 2012.
Tingberg A, Förnvik D, Mattsson S, et al. Breast cancer screening with tomosynthesis – initial experiences. Radiat Prot Dosimetry. 2011;147(1–2):180–3.
Gennaro G, Toledano A, di Maggio C, et al. Digital breast tomosynthesis versus digital mammography: a clinical performance study. Eur Radiol. 2010;20:1545–53.
Poplack SP, Tosteson TD, Kogel CA, et al. Digital breast tomosynthesis: initial experience in 98 women with abnormal digital screening mammography. AJR Am J Roentgenol. 2007;189:616–23.
Kopans D, Gavenonis S, Halpern E, et al. Calcifications in the breast and digital breast tomosynthesis. Breast J. 2011;17:638–44.
Spangler ML, Zuley ML, Sumkin JH, et al. Detection and classification of calcifications on digital breast tomosynthesis and 2D digital mammography: a comparison. AJR Am J Roentgenol. 2011;196:320–4.
Gur D, Abrams GS, Chough DM, et al. Digital breast tomosynthesis: observer performance study. AJR Am J Roentgenol. 2009;193:586–91.
Gur D, Sumkin J, Zuley M, et al. Recall rate reduction with tomosynthesis during baseline examinations: preliminary assessment from a prospective screening trial. Presented at Radiological Society of North America 2011 scientific assembly and annual meeting, Chicago, IL. rsna2011.rsna.org/search/event_display.cfm?am_id=2&em_id=11004417&printmode=Y&autoprint=N
Noroozian M, Hadjiiski L, Rahnama-Moghadam S, et al. Digital breast tomosynthesis is comparable to mammographic spot views for mass characterization. Radiology. 2012;262:61–8.
Tagliafico A, Astengo D, Cavagnetto F, et al. One-to-one comparison between digital spot compression view and digital breast tomosynthesis. Eur Radiol. 2012;22(3):539–44.
Hakim CM, Chough DM, Ganott MA, et al. Digital breast tomosynthesis in the diagnostic environment: a subjective side-by-side review. AJR Am J Roentgenol. 2010;195:172–6.
Position Statement of the Health Physics Society—Radiation Risk in Perspective. 2010.
Kopans D, Moore R. Digital breast tomosynthesis (DBT) NCI 3000-Women Trial. Presented at the 95th scientific assembly and annual meeting of the Radiological Society of North America, Chicago, IL, 30 Nov 2009. Abstract SSE01-01.
Good WJ, Abrams GS, Catullo VJ, et al. Digital breast tomosynthesis: a pilot observer study. AJR Am J Roentgenol. 2008;190:865–9.
National Center for Health Statistics. Health, United States, 2011: with special feature on socioeconomic status and health. Hyattsville, MD: National Center for Health Statistics; 2012.
Saunders RS, Samei E, Lo JY, et al. Can compression be reduced for breast tomosynthesis? Monte Carlo Study on mass and microcalcification conspicuity in tomosynthesis. Radiology. 2009;251:673–82.
Förnvik D, Andersson I, Svahn T, et al. The effect of reduced breast compression in breast tomosynthesis: human observer study using clinical cases. Radiat Prot Dosimetry. 2010;139(1–3):118–23.
Chen SC, Carton AK, Albert M, et al. Initial clinical experience with contrast-enhanced digital breast tomosynthesis. Acad Radiol. 2007;14:229–38.
Williams MB, Judy PG, Gunn S, et al. Dual-modality breast tomosynthesis. Radiology. 2010;255:191–8.
Fang Q, Selb J, Carp SA, et al. Combined optical and X-ray tomosynthesis breast imaging. Radiology. 2011;258:89–97.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2014 Springer Science+Business Media New York
About this chapter
Cite this chapter
Levine, G., Lopez, J. (2014). Digital Breast Tomosynthesis. In: Francescatti, D., Silverstein, M. (eds) Breast Cancer. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-8063-1_9
Download citation
DOI: https://doi.org/10.1007/978-1-4614-8063-1_9
Published:
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4614-8062-4
Online ISBN: 978-1-4614-8063-1
eBook Packages: MedicineMedicine (R0)