Solid-State Fermentation of Agricultural Residues for the Production of Antibiotics

  • Ganesh Kumar ArumugamEmail author
  • Venkatesh Selvaraj
  • Dharani Gopal
  • Kirubagaran Ramalingam


The increasing demand in pharmaceutical products for human welfare has encouraged remarkable attempts towards the development of biotechnological processes for the production of antibiotics using readily available agricultural residues. Immense availability and cost-effectiveness of agricultural residues compared to sugars offer greater advantages in commercial usage. However, these constituents are currently underutilised. Productions of antibiotics have been carried out by both solid-state fermentation (SSF) and submerged fermentation (SmF) using wide range of microorganisms. The advancement in the field of SSF and its advantage over SmF has opened its application for production of antibiotics utilising low carbon and energy sources. This chapter gives an insight on various approaches that are being carried out for antibiotic production using SSF. The biotechnological potential of lignocellulosic biomass, factors affecting the production and yield of antibiotics from specific microorganisms are accounted.


Secondary Metabolite Sugarcane Bagasse Wheat Bran Antibiotic Production Shikimic Acid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



The authors gratefully acknowledge the financial support given by the Earth System Science Organization, Ministry of Earth Sciences, Government of India. The authors are thankful to the Director, National Institute of Ocean Technology (NIOT), Ministry of Earth Sciences, Govt. of India, for his constant support and encouragement for preparation of this chapter. The authors are also thankful to all the scientific and supporting staffs of Marine Biotechnology, NIOT, Chennai, for their support.


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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • Ganesh Kumar Arumugam
    • 1
    Email author
  • Venkatesh Selvaraj
    • 1
  • Dharani Gopal
    • 1
  • Kirubagaran Ramalingam
    • 1
  1. 1.Marine BiotechnologyNational Institute of Ocean Technology (Ministry of Earth Sciences, Govt. of India)ChennaiIndia

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