Granulocytic Sarcoma

  • Roberto N. Miranda
  • Joseph D. Khoury
  • L. Jeffrey Medeiros
Part of the Atlas of Anatomic Pathology book series (AAP)


Granulocytic sarcoma is an extramedullary tumor mass composed predominantly of immature granulocytic cells with more or less evidence of maturation. Older terms for this entity included chloroma and extramedullary myeloid cell tumor. Most pathologists use the World Health Organization (WHO) term myeloid sarcoma for tumor masses composed of granulocytic and monocytic precursors; however, in this Atlas, we discuss these neoplasms separately and emphasize their distinct clinical, cytogenetic, and molecular features. Perivascular or interstitial infiltrates of leukemic blasts, without formation of a tumor mass, are not included in the definition of granulocytic (or monocytic) sarcoma.


Acute Myeloid Leukemia Chronic Myelogenous Leukemia Granulocytic Sarcoma Myeloid Sarcoma Granulocytic Differentiation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Roberto N. Miranda
    • 1
  • Joseph D. Khoury
    • 1
  • L. Jeffrey Medeiros
    • 1
  1. 1.Department of HematopathologyThe University of Texas M.D. Anderson Cancer CenterHoustonUSA

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