Granulocytic sarcoma is an extramedullary tumor mass composed predominantly of immature granulocytic cells with more or less evidence of maturation. Older terms for this entity included chloroma and extramedullary myeloid cell tumor. Most pathologists use the World Health Organization (WHO) term myeloid sarcoma for tumor masses composed of granulocytic and monocytic precursors; however, in this Atlas, we discuss these neoplasms separately and emphasize their distinct clinical, cytogenetic, and molecular features. Perivascular or interstitial infiltrates of leukemic blasts, without formation of a tumor mass, are not included in the definition of granulocytic (or monocytic) sarcoma.
KeywordsAcute Myeloid Leukemia Chronic Myelogenous Leukemia Granulocytic Sarcoma Myeloid Sarcoma Granulocytic Differentiation
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