Mycobacterial Spindle Cell Pseudotumor

  • Roberto N. Miranda
  • Joseph D. Khoury
  • L. Jeffrey Medeiros
Part of the Atlas of Anatomic Pathology book series (AAP)


Mycobacterial spindle cell pseudotumor is a form of granulomatous inflammation in response to infection by mycobacterial species in which histiocytes exhibit spindle cell morphology. Mycobacterial spindle cell pseudotumor is a rare form of mycobacterial lymphadenopathy, also termed histoid form, most commonly caused by Mycobacterium avium-intracellulare complex (MAC) and, to a lesser extent, M. leprae and M. tuberculosis. The majority of patients are immunocompromised, usually with acquired immunodeficiency syndrome (AIDS). Although most cases of mycobacterial spindle cell tumor involve lymph nodes, involvement of skin, spleen, and brain can also be seen.


Public Health Differential Diagnosis Growth Pattern Spindle Cell Acquire Immunodeficiency Syndrome 
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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Roberto N. Miranda
    • 1
  • Joseph D. Khoury
    • 1
  • L. Jeffrey Medeiros
    • 1
  1. 1.Department of HematopathologyThe University of Texas M.D. Anderson Cancer CenterHoustonUSA

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